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On the panel

Vitamin E — 7.4 mg

The antioxidant that works by putting itself in the way.

What It Is

Vitamin E is not one molecule but a family of eight, four tocopherols and four tocotrienols. Only alpha-tocopherol is preferentially retained by a transfer protein in the liver, which is why it is the form that counts nutritionally and the form printed on labels.

It is fat soluble, and that is the entire point of it: it dissolves into the fatty interior of a cell membrane and stays there, which is exactly where the damage it prevents takes place.

02 / The role

What It Actually Does

Three jobs, described without the marketing vocabulary.

It ends the chain rather than one attacker

Membranes are built from polyunsaturated fats that oxidise in chain reactions, each damaged molecule attacking its neighbour. Alpha-tocopherol steps in front of the chain and absorbs it, so a single molecule can protect a great many membrane lipids by stopping the propagation.

It works in a pair

Spent vitamin E is restored by vitamin C from the watery side of the membrane. A panel that carries one and not the other is doing half the job.

It reaches the surface in sebum

Vitamin E is secreted onto the skin surface in sebum, forming part of the outermost antioxidant defence against ultraviolet light and pollution. Sun exposure depletes it, which means that layer is consumed on exactly the days it is most needed.

Vitamin E as it appears in Gelagen

7.4 mg In Every Serving

Our serving carries 7.4 mg of alpha-tocopherol against an adult requirement of around 15 mg a day. Most diets containing nuts, seeds or vegetable oils meet that comfortably, so this is a supporting figure that keeps the recycling loop with vitamin C intact rather than an attempt to flood the system.

Membrane fats oxidise in chains, each damaged molecule attacking the next along the membrane. Alpha-tocopherol dissolves into that same fatty layer and absorbs the reaction, ending the chain instead of neutralising one attacker. Vitamin C then restores it from the watery side, which is why the two are worth carrying together.

Who Tends To Fall Short

Deficiency is rare in people eating normally, because vitamin E is abundant in nuts, seeds and cooking oils. Where it occurs it is nearly always secondary to a condition impairing fat absorption: cystic fibrosis, Crohn's disease, cholestatic liver disease, or surgery that shortened the small intestine.

The signs are neurological before they are cutaneous — poor coordination, muscle weakness, disturbed sensation in hands and feet.

Where It Turns Up In Food

Sources of Vitamin E
SourceRoughlyNotes
Sunflower seeds~7.4 mg per 30 gA small handful matches our whole serving
Almonds~6.8 mg per 30 gConsistently among the densest sources
Sunflower oil~5.6 mg a tablespoonCooking oil does most of the work in a typical diet
Hazelnuts~4.3 mg per 30 gUseful and easy
Avocado~2.7 mg eachModest, and popular enough to count
Cooked spinach~1.9 mg per half cupSmall contributions, frequently

The Ceiling, And The Cautions

The adult upper limit is 1000 mg a day for supplemental alpha-tocopherol, so our 7.4 mg is a fraction of one percent of it.

One caution is worth naming even at this level. Vitamin E in high supplemental doses has an antiplatelet effect and can add to the action of warfarin, aspirin or other blood thinners. At the amount on this panel that is not a practical concern, but mention it to a doctor if you are anticoagulated and also taking something else containing vitamin E.

Where This Comes From

  • Alpha-tocopherol transfer protein in the liver is why the alpha form is the one retained.
  • The tocopherol-ascorbate recycling couple is well described in membrane biochemistry.
  • Deficiency in humans is almost always secondary to fat malabsorption rather than to dietary shortage.

General nutritional science rather than claims about this product. Nothing on this page is medical advice; see our disclaimer.

05 / Answers

Vitamin E Questions

What we get asked about this line of the label specifically.

Should I rub vitamin E oil on scars instead?

Topical vitamin E is a reasonable emollient and a poor scar treatment; the scar studies are unimpressive and contact dermatitis is not unusual. Vitamin E taken by mouth is working somewhere else entirely, inside membranes.

Natural or synthetic?

The natural form is retained rather better by the liver transfer protein, which is why labels distinguish them. Across the sort of figure a daily panel carries, that gap barely registers.

Does it prevent wrinkles?

No supplement prevents wrinkles. Antioxidants plausibly reduce part of the oxidative load skin carries, and sunscreen does far more for the same outcome.

Can I take it with fish oil?

Yes, and a good many fish oil capsules already carry vitamin E to stop the oil turning. Read that label too and total the two figures.